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Pneumocytes

Pneumocytes (or alveolar cells) are the cells that line the alveoli and comprise of the majority of the inner surface of the lungs

  • There are two types of alveolar cells – type I pneumocytes and type II pneumocytes

Type I Pneumocytes:

  • Type I pneumocytes are involved in the process of gas exchange between the alveoli and the capillaries

  • They are squamous (flattened) in shape and extremely thin (~ 0.15µm) – minimising the diffusion distance for respiratory gases

  • The cells are connected by occluding junctions, which prevents the leakage of tissue fluid into the alveolar air space

Type II Pneumocytes:

  • Type II pneumocytes secrete pulmonary surfactant, which reduces surface tension in the alveoli (making it easier for them to inflate)

  • They are cuboidal in shape and possess many granules called lamellar bodies (which store the surfactant)

Types of Alveolar Cells
pneumocyte
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