

Pneumocytes (or alveolar cells) are the cells that line the alveoli and comprise of the majority of the inner surface of the lungs
There are two types of alveolar cells – type I pneumocytes and type II pneumocytes
Type I Pneumocytes:
Type I pneumocytes are involved in the process of gas exchange between the alveoli and the capillaries
They are squamous (flattened) in shape and extremely thin (~ 0.15µm) – minimising the diffusion distance for respiratory gases
The cells are connected by occluding junctions, which prevents the leakage of tissue fluid into the alveolar air space
Type II Pneumocytes:
Type II pneumocytes secrete pulmonary surfactant, which reduces surface tension in the alveoli (making it easier for them to inflate)
They are cuboidal in shape and possess many granules called lamellar bodies (which store the surfactant)

