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Blastocysts

Following the fusion of an egg and sperm, the diploid zygote will undergo several mitotic divisions to form a solid ball of cells called a morula

  • As the morula continues to divide, it undergoes differentiation and cavitation (cavity formation) to form a blastocyst

A blastocyst is comprised of three distinct sections:

  • An inner cell mass (that will develop into the embryo)

  • A surrounding outer layer called the trophoblast (this will develop into the placenta)

  • A fluid filled cavity called the blastocoele

The blastocyst travels via the oviduct to the uterus and implants into the endometrial lining (~ one week post fertilisation)

  • Digestive enzymes are released to degrade the endometrial lining, while autocrine hormones trigger implantation into the uterine wall

  • Once implanted, the blastocyst can derive nutrition from the endometrial tissue fluid and continue to the next stage of embryonic development

Blastocyst Development
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